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| phosphatidylcholine transfer protein ： ウィキペディア英語版 |
phosphatidylcholine transfer protein
Phosphatidylcholine transfer protein (PCTP) also known as StAR-related lipid transfer domain protein 2 (STARD2) is a specific intracellular phospholipid binding protein that can transfer phosphatidylcholine between different membranes in the cytosol.
In humans, phosphatidylcholine transfer protein is encoded by the ''PCTP'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=58488 )〕
==Function==
PCTP transfers phosphatidylcholine molecules between membranes ''in vitro''.〔 Further studies found that sensitivity to phosphatidylcholine levels causes PCTP to interact with select enzymes, promoting their activation. PCTP stimulates the acyl-CoA thioesterase activity of thioesterase superfamily member 2 (Them2)/acyl-CoA thioesterase 13 (ACOT13) and the activity of homeodomain transcription factor paired box gene 3 (PAX3). Protein kinase C phosphorylation promotes localization of PCTP to the mitochondrion where it may activate Them2.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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